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A Prospect on Research and Application of Natural Toxins

Chen Yisheng

Strategic Study of CAE 2003, Volume 5, Issue 2,   Pages 16-19

Abstract: They display plentiful diversities in many aspects such as biogenity, chemical structure, biological

Keywords： natural toxins     diversity in natural toxins     control of biological toxicosis     biogenic syntheses     chemical    

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PRODUCTION OF NEW WAP-8294A CYCLODEPSIPEPTIDES BY THE BIOLOGICAL CONTROL AGENT LYSOBACTER ENZYMOGENES

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 1,   Pages 120-132 doi: 10.15302/J-FASE-2021410

Abstract:

Naturally-occurring environmental microorganisms may provide ‘green’ and effective biocontrol tools for disease management in agricultural crops. Due to the constant threat of resistant pathogens there is a pressing and continual need to search for new biocontrol tools. This study investigated the production of new analogs of WAP-8294A compounds by the biocontrol agent Lysobacter enzymogenes OH11 through biosynthetic engineering. WAP-8294As are a family of natural cyclic lipodepsipeptides with potent activity against Gram-positive bacteria. A series of genetic manipulations was therefore conducted on the accessory genes in the WAP biosynthetic gene cluster. The resulting strains containing a single-point mutation in ORF4, which was predicted to encode a 2-ketoglutarate dependent dioxygenase, produced deoxy-WAP-8294As. This result provides evidence for the function of ORF4 in catalyzing β-hydroxylation of the D-asparagine residue in WAP-8294As. In addition, six new analogs of WAP-8294As were identified by UHPLC-HR-MS/MS. This is the first attempt to produce new WAP-8294As in Lysobacter and shows that the spectrum of the biocontrol compounds may be expanded through the manipulation of biosynthetic genes.

 

Keywords： biocontrol / biosynthesis / Lysobacter / natural products / WAP-8294A    

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Influence of Survivin-targeted siRNA on the biological features of colorectal carcinoma cells

XIONG Ying, GUO Wen, LI Ting, LI Ke

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 304-307 doi: 10.1007/s11684-007-0058-7

Abstract: The transient transfection of survivin-targeted siRNA to Lovo cells and its influence on the biologicalgroups (Survivin-1 group and Survivin-2 group) respectively decreased by 70% and 39.1% compared with the controltransfection, apoptosis rates of the two RNAi groups were 21.51% and 26.28%, both of which were higher than control490 nm of the two RNAi groups was 0.581±0.070 and 0.681±0.104, both of which were much lower than the control

Keywords： control     therapy     influence     Survivin-1     colorectal carcinoma    

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Machinability of ultrasonic vibration-assisted micro-grinding in biological bone using nanolubricant

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0717-z

Abstract: These results showed that U-NJMC provides a novel approach for clinical surgical micro-grinding of biological

Keywords： micro-grinding     biological bone     ultrasonic vibration (UV)     nanoparticle jet mist cooling (NJMC)     grinding    

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Microorganism-derived biological macromolecules for tissue engineering

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 358-377 doi: 10.1007/s11684-021-0903-0

Abstract: According to literature, certain microorganism productions mediate biological effects.The present review aims to introduce microorganism-derived biological macromolecules, such as pullulanGrowing evidence indicates that these materials can be used as biological material in scaffolds to enhance

Keywords： biological macromolecules     regenerative medicine     tissue engineering     exopolysaccharide     carbohydrate    

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Low intensity ultrasound stimulates biological activity of aerobic activated sludge

LIU Hong, YAN Yixin, WANG Wenyan, YU Yongyong

Frontiers of Environmental Science & Engineering 2007, Volume 1, Issue 1,   Pages 67-72 doi: 10.1007/s11783-007-0013-5

Abstract: This work aims to explore a procedure to improve biological wastewater treatment efficiency using low

Keywords： sonication     irradiation     kHz     treatment efficiency     AS activity    

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Biological conversion pathways of sulfate reduction ammonium oxidation in anammox consortia

Zhen Bi, Deqing Wanyan, Xiang Li, Yong Huang

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 3, doi: 10.1007/s11783-019-1217-1

Abstract: Thus, the hypothesis of biological conversion pathways of ammonium and sulfate in anammox consortia is

Keywords： Anammox bacteria     Autotrophic     Biological conversion     Sulfate reducing ammonium oxidation (SRAO)    

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Overlooked nitrogen-cycling microorganisms in biological wastewater treatment

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1426-2

Abstract:

• AOA and comammox bacteria can be more abundant and active than AOB/NOB at WWTPs.

Keywords： Ammonia oxidizing archaea (AOA)     Complete ammonia oxidizing (comammox) bacteria     Dissimilatory nitrate reduction to ammonium (DNRA) bacteria     Nitrate/nitrite-dependent anaerobic methane oxidizing (NOx-DAMO) microorganisms     Engineering application    

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Mechanical behavior and semiempirical force model of aerospace aluminum alloy milling using nano biological

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0720-4

Abstract: Aerospace aluminum alloy is the most used structural material for rockets, aircraft, spacecraft, and space stations. The deterioration of surface integrity of dry machining and the insufficient heat transfer capacity of minimal quantity lubrication have become the bottleneck of lubrication and heat dissipation of aerospace aluminum alloy. However, the excellent thermal conductivity and tribological properties of nanofluids are expected to fill this gap. The traditional milling force models are mainly based on empirical models and finite element simulations, which are insufficient to guide industrial manufacturing. In this study, the milling force of the integral end milling cutter is deduced by force analysis of the milling cutter element and numerical simulation. The instantaneous milling force model of the integral end milling cutter is established under the condition of dry and nanofluid minimal quantity lubrication (NMQL) based on the dual mechanism of the shear effect on the rake face of the milling cutter and the plow cutting effect on the flank surface. A single factor experiment is designed to introduce NMQL and the milling feed factor into the instantaneous milling force coefficient. The average absolute errors in the prediction of milling forces for the NMQL are 13.3%, 2.3%, and 7.6% in the x-, y-, and z-direction, respectively. Compared with the milling forces obtained by dry milling, those by NMQL decrease by 21.4%, 17.7%, and 18.5% in the x-, y-, and z-direction, respectively.

Keywords： milling     force     nanofluid minimum quantity lubrication     aerospace aluminum alloy     nano biological lubricant    

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ROOT EXUDATES FROM CANOLA EXHIBIT BIOLOGICAL NITRIFICATION INHIBITION AND ARE EFFECTIVE IN INHIBITING

Frontiers of Agricultural Science and Engineering 2022, Volume 9, Issue 2,   Pages 177-186 doi: 10.15302/J-FASE-2021421

Abstract: This biological nitrification inhibition (BNI) capacity can decrease N loss and increase N uptake from

Keywords： ammonia oxidizing microorganisms / biological nitrification inhibition / farming rotations / nitrogen    

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Quorum sensing regulation methods and their effects on biofilm in biological waste treatment systems:

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 7, doi: 10.1007/s11783-021-1495-2

Abstract:

• Quorum sensing enhancement and inhibition methods are summarized.

Keywords： Quorum sensing     Biological waste treatment     Biofilm formation    

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Inhibition character of crotonaldehyde manufacture wastewater on biological acidification

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 6, doi: 10.1007/s11783-021-1403-9

Abstract:

• The inhibition of the main organic pollutions in CMW was demonstrated.

Keywords： Crotonaldehyde manufacture wastewater     Biological acidification     Volatile fatty acids     Inhibition     Toxic    

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Circulating fluidized bed biological reactor for nutrients removal

CUI Yubo, LIU Hongbo, BAI Chunxue

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 3,   Pages 349-353 doi: 10.1007/s11783-008-0051-7

Abstract: A new biological nitrogen removal process, which is named herein “The circulating fluidized bed bioreactor

Keywords： soluble chemical     bioreactor     biological nitrogen     optimum nitrified     nitrogen removal    

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Comparison of membrane fouling in ultrafiltration of down-flow and up-flow biological activated carbon

Lu Ao, Wenjun Liu, Yang Qiao, Cuiping Li, Xiaomao Wang

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 6, doi: 10.1007/s11783-018-1046-7

Abstract:

The UF membrane fouling by down- and up-flow BAC effluents were compared.

Up-flow BAC effluent fouled the membrane faster than down-flow BAC effluent.

The combined effects dominated irreversible fouling.

The extent of fouling exacerbated by inorganic particles was higher.

Keywords： Ultrafiltration     Membrane fouling     Down-flow biological activated carbon     Up-flow biological activated carbon    

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Development Trends of Chemical and Biological Weapons and Defense Technology in the 21st Century

Chen Jisheng

Strategic Study of CAE 2000, Volume 2, Issue 11,   Pages 25-28

Abstract:

The medical protection of chemical and biological ( CB ) weapons is one of the most important categoriesAn realized risk of chemical and biological threat still remain in the 21st century.

Keywords： chemical and biological weapon     chemical and biological defense     medical protection     chemical and biological    

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Title Author Date Type Operation

A Prospect on Research and Application of Natural Toxins

Chen Yisheng

Journal Article

PRODUCTION OF NEW WAP-8294A CYCLODEPSIPEPTIDES BY THE BIOLOGICAL CONTROL AGENT LYSOBACTER ENZYMOGENES

Journal Article

Influence of Survivin-targeted siRNA on the biological features of colorectal carcinoma cells

XIONG Ying, GUO Wen, LI Ting, LI Ke

Journal Article

Machinability of ultrasonic vibration-assisted micro-grinding in biological bone using nanolubricant

Journal Article

Microorganism-derived biological macromolecules for tissue engineering

Journal Article

Low intensity ultrasound stimulates biological activity of aerobic activated sludge

LIU Hong, YAN Yixin, WANG Wenyan, YU Yongyong

Journal Article

Biological conversion pathways of sulfate reduction ammonium oxidation in anammox consortia

Zhen Bi, Deqing Wanyan, Xiang Li, Yong Huang

Journal Article

Overlooked nitrogen-cycling microorganisms in biological wastewater treatment

Journal Article

Mechanical behavior and semiempirical force model of aerospace aluminum alloy milling using nano biological

Journal Article

ROOT EXUDATES FROM CANOLA EXHIBIT BIOLOGICAL NITRIFICATION INHIBITION AND ARE EFFECTIVE IN INHIBITING

Journal Article

Quorum sensing regulation methods and their effects on biofilm in biological waste treatment systems:

Journal Article

Inhibition character of crotonaldehyde manufacture wastewater on biological acidification

Journal Article

Circulating fluidized bed biological reactor for nutrients removal

CUI Yubo, LIU Hongbo, BAI Chunxue

Journal Article

Comparison of membrane fouling in ultrafiltration of down-flow and up-flow biological activated carbon

Lu Ao, Wenjun Liu, Yang Qiao, Cuiping Li, Xiaomao Wang

Journal Article

Development Trends of Chemical and Biological Weapons and Defense Technology in the 21st Century

Chen Jisheng

Journal Article